SIMOA HD-X™ ANALYZER

DELIVERING ULTRASENSITIVE BIOMARKER MEASUREMENT YOU CAN COUNT ON!

The Simoa HD-X Analyzer™ is the latest model of the fully automated Simoa bead-based immunoassay platform. Re-engineered, the platform’s ultra-sensitivity and dependability empower researchers with 1000x greater sensitivity than traditional immunoassays. Leveraging years of experience with the ground-breaking Simoa HD-1 analyzer, the HD-X delivers increased productivity, user flexibility, unparalleled sensitivity and best in class assay performance.

The Simoa bead-based technology isolates each bead-immunocomplex to allow for enzyme bound to the capture antibody to produce sufficient fluorescence in each well to be detectable, even when just a single molecule is present. As a result, the analyzer produces a map of the array—each of which contains more than 200,000 wells—where each well can be digitally analyzed as either “on” (containing a target molecule) or “off”. The proprietary Simoa algorithm then converts the measurement into a concentration which reaches femtomolar levels for most analytes. This revolutionary approach to digitalizing ELISA offers on average a 1000-fold improvement in sensitivity over current immunoassay techniques.

Key features include:

• Ultra-sensitivity – Up to 1000x greater sensitivity than traditional immunoassays
• Automation – Reproducibility and convenience of sample->answer workflow
• Multiplexing – Measure up to 6 biomarkers in single sample at fg/ml concentrations
• Flexibility – Supports both highthroughput and rapid result workflows
• Efficiency – Precise control of assay conditions allows for use of stored assay calibration values
• Menu – Fully compatible with 80+ assays also available on HD-1 as well as customized homebrew assays
• Regulatory Compliance – Enables 21CFR Part 11 compliance with streamlined run reports and user management