Cell Metric® CLD System

High throughput High Resolution Imaging tool to accelerate upstream cell line development

The Cell Metric® CLD is a high resolution high-throughput bench-top imaging system specifically designed to offer an alternative approach for ensuring cell line monoclonality and to speed up Cell Line Development (CLD). The Cell Metric® CLD system apart from its unique cell imaging and image analysis capabilities includes an integrated, temperature-controlled plate stacker. A batch of up to 10 lidded plates can be loaded manually into the stacker and the plates are automatically transferred for imaging one at a time with barcode reading. It is ideal for groups typically having throughput requirements from tens to hundreds of plates.

The Cell Metric® CLD uses non-invasive brightfield imaging for analysis of settled suspension or adherent cells. . This semi-automated image documentation can be used to prove and document mono-clonality in a regulatory compliant manner by providing a permanent record of evidence with photo documentation of cell growth and development from day 1.

Cell Metric imparts following advantages-

• High Brightfeild image resolution enables to very well segregatedpair of cells
• Automatic focusing ensures clear images
• High precision XYZ positioning system
• Uniform imaging upto the well edge
• High throughput in imaging a batch of 10plates at a time
• Temperature control
• A complete audit trail report with photo documentation of cell growth and cell development from day 1

The Cell Metric® CLD can now be purchased with fluorescence detection features that enable the user to validate a new a seeding method or quality check their existing method.